Fut7^tm1Jbl
Targeted Allele Detail

Summary

• Symbol: Fut7^tm1Jbl
• Name: fucosyltransferase 7; targeted mutation 1, John Lowe
• MGI ID: MGI:2387664
• Synonyms: FucT-VII (-)
• Gene: Fut7 Location: Chr2:25313279-25316386 bp, + strand Genetic Position: Chr2, 17.25 cM
• Alliance: Fut7^tm1Jbl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:35023
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Sequence encoding the catalytic domain was disrupted by the insertion of a PGK-neo cassette. (J:35023)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fut7 Mutation: 15 strains or lines available

References

• Original: J:35023 Maly P, et al., The alpha(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis. Cell. 1996 Aug 23;86(4):643-53
• All: 55 reference(s)