Cdh6^tm1Nosu
Targeted Allele Detail

Summary

• Symbol: Cdh6^tm1Nosu
• Name: cadherin 6; targeted mutation 1, Noriko Osumi
• MGI ID: MGI:2387681
• Gene: Cdh6 Location: Chr15:13028787-13173761 bp, - strand Genetic Position: Chr15, 6.11 cM
• Alliance: Cdh6^tm1Nosu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:67150
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: The gene was disrupted by insertion of a PGK-neo cassette (in reverse orientation) into exon 1. Absence of gene expression in homozygous mutants was confirmed by Western blot analysis of whole brain homogenates from postnatal day 7 animals. (J:67150)

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdh6 Mutation: 40 strains or lines available

References

• Original: J:67150 Inoue T, et al., Role of cadherins in maintaining the compartment boundary between the cortex and striatum during development. Development. 2001 Feb;128(4):561-9
• All: 2 reference(s)