Etv4^tm1Arbr
Targeted Allele Detail

Summary

• Symbol: Etv4^tm1Arbr
• Name: ets variant 4; targeted mutation 1, Silvia Arber
• MGI ID: MGI:2387770
• Synonyms: Etv4^-, Etv4^lacZ, Pea3^nlslacZ, Pea3^NLZ
• Gene: Etv4 Location: Chr11:101660568-101676197 bp, - strand Genetic Position: Chr11, 65.48 cM
• Alliance: Etv4^tm1Arbr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:78717
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A portion of exon 6 and all of exons 7 through 11 were replaced with a cassette containing IRES-NLS-lacZ followed by a polyadenylation signal and neo gene. (J:78717)

Expression

In Mice Carrying this Mutation:	32 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Etv4^tm1Arbr

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Etv4 Mutation: 41 strains or lines available

References

• Original: J:78717 Livet J, et al., ETS gene Pea3 controls the central position and terminal arborization of specific motor neuron pools. Neuron. 2002 Aug 29;35(5):877-92
• All: 22 reference(s)