Mixl1^tm1Robb
Targeted Allele Detail

Summary

• Symbol: Mixl1^tm1Robb
• Name: Mix paired-like homeobox; targeted mutation 1, Lorraine Robb
• MGI ID: MGI:2387828
• Synonyms: Mixl1^-
• Gene: Mixl1 Location: Chr1:180520608-180524599 bp, - strand Genetic Position: Chr1, 84.46 cM
• Alliance: Mixl1^tm1Robb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:77443
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding region of exon 1 was replaced by a cassette containing GFP and a floxed neo gene. GFP expression was driven by the endogenous promoter. (J:77443)

Expression

In Structures Affected by this Mutation:

12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mixl1 Mutation: 20 strains or lines available

References

• Original: J:77443 Hart AH, et al., Mixl1 is required for axial mesendoderm morphogenesis and patterning in the murine embryo. Development. 2002 Aug;129(15):3597-608
• All: 1 reference(s)