Vav1tm1Bbd
Targeted Allele Detail
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| Symbol: |
Vav1tm1Bbd |
| Name: |
vav 1 oncogene; targeted mutation 1, Mariano Barbacid |
| MGI ID: |
MGI:2387839 |
| Synonyms: |
vav (-) |
| Gene: |
Vav1 Location: Chr17:57586100-57635031 bp, + strand Genetic Position: Chr17, 29.76 cM
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| Alliance: |
Vav1tm1Bbd page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:22517
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| Parent Cell Line: |
D3 (ES Cell)
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| Strain of Origin: |
129S2/SvPas
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Sequences encoding amino acids 135-195 comprising the entire acidic domain were replaced with a PGK-neo cassette via homologous recombination. Homozygous mutant embryos were identified by PCR genotype analysis at day E3.5, but not at days E7.5-E12.5.
(J:22517)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Vav1 Mutation: |
60 strains or lines available
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| Original: |
J:22517 Zmuidzinas A, et al., The vav proto-oncogene is required early in embryogenesis but not for hematopoietic development in vitro. EMBO J. 1995 Jan 3;14(1):1-11 |
| All: |
1 reference(s) |
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Analysis Tools
