Atp7a^Mo-1Pub
Radiation induced Allele Detail

Summary

• Symbol: Atp7a^Mo-1Pub
• Name: ATPase, copper transporting, alpha polypeptide; mottled Oak Ridge 1Pub
• MGI ID: MGI:2387944
• Synonyms: Atp7a^mo1Pub
• Gene: Atp7a Location: ChrX:105070882-105168532 bp, + strand Genetic Position: ChrX, 47.36 cM
• Alliance: Atp7a^Mo-1Pub page

Mutation origin

• Strain of Origin: T STOCK x (101 x C3H)F1

Mutation description

• Allele Type: Radiation induced
• Mutation: Single point mutation
• Mutation details: An induced mutation that was created at The Oak Ridge National Laboratory. A G-to-A mutation at the +1 splice donor site of intron 14 resulted in the skipping of exon 14 in the transcript expressed from this allele. The deleted sequences encode the putative fifth transmemebrane domain. (J:38977)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atp7a Mutation: 69 strains or lines available

Notes

The mutation was induced by plutonium citrate.

References

• Original: J:38977 Cecchi C, et al., The mottled mouse as a model for human Menkes disease: identification of mutations in the Atp7a gene. (Correction: vol. 6(5):829). Hum Mol Genet. 1997 Mar;6(3):425-33
• All: 1 reference(s)