Atp7a^Mo-7ENURF
Chemically induced Allele Detail

Summary

• Symbol: Atp7a^Mo-7ENURF
• Name: ATPase, copper transporting, alpha polypeptide; mottled Oak Ridge 7ENURF
• MGI ID: MGI:2387952
• Synonyms: Atp7a^mo7ENURF
• Gene: Atp7a Location: ChrX:105070882-105168532 bp, + strand Genetic Position: ChrX, 47.36 cM
• Alliance: Atp7a^Mo-7ENURF page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• Mutation details: An induced mutation that was created at The Oak Ridge National Laboratory. Reduced levels of transcript are reported to be expressed from this allele.
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atp7a Mutation: 69 strains or lines available

Notes

This mutation reduces Atp7a transcription in heterozygous females and is lethal to hemizygous male embryos (J:38977).

References

• Original: J:38977 Cecchi C, et al., The mottled mouse as a model for human Menkes disease: identification of mutations in the Atp7a gene. (Correction: vol. 6(5):829). Hum Mol Genet. 1997 Mar;6(3):425-33
• All: 1 reference(s)