Slc31a1^tm1Jgt
Targeted Allele Detail

Summary

• Symbol: Slc31a1^tm1Jgt
• Name: solute carrier family 31, member 1; targeted mutation 1, Jane Gitschier
• MGI ID: MGI:2388122
• Synonyms: Ctr1^-
• Gene: Slc31a1 Location: Chr4:62278964-62310006 bp, + strand Genetic Position: Chr4, 33.11 cM, cytoband C1-C2
• Alliance: Slc31a1^tm1Jgt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:69862
• Parent Cell Line: JM-1 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding region of the gene (exon 1-4) was deleted and replaced with a lacZ-neo cassette via homologous recombination. Homozygous mutant embryos were observed up to day E9.5. (J:69862)

Expression

In Mice Carrying this Mutation:	6 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc31a1 Mutation: 40 strains or lines available

References

• Original: J:69862 Kuo YM, et al., The copper transporter CTR1 provides an essential function in mammalian embryonic development. Proc Natl Acad Sci U S A. 2001 Jun 5;98(12):6836-41
• All: 1 reference(s)