Il4^tm1.1Wep
Targeted Allele Detail

Summary

• Symbol: Il4^tm1.1Wep
• Name: interleukin 4; targeted mutation 1.1, William E Paul
• MGI ID: MGI:2388164
• Synonyms: G4, GFP/IL4, Il4^eGFP, Il4^G4, IL-4/GFP
• Gene: Il4 Location: Chr11:53503287-53509492 bp, - strand Genetic Position: Chr11, 31.97 cM
• Alliance: Il4^tm1.1Wep page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:67964
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: This allele is a derivative of Il4^tm1Wep. The floxed neo cassette was removed by mating mutant animals to a transgenic line expressing cre recombinase in the oocytes, leaving behind a loxP site and the GFP knock-in cassette in place of exon 1. (J:67964)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il4 Mutation: 46 strains or lines available

References

• Original: J:67964 Hu-Li J, et al., Regulation of expression of IL-4 alleles: analysis using a chimeric GFP/IL-4 gene. Immunity. 2001 Jan;14(1):1-11
• All: 26 reference(s)