Pde6b^rd10
Spontaneous Allele Detail

Summary

• Symbol: Pde6b^rd10
• Name: phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide; retinal degeneration 10
• MGI ID: MGI:2388259
• Synonyms: Pde6b^rd1-J, rd10
• Gene: Pde6b Location: Chr5:108536239-108579609 bp, + strand Genetic Position: Chr5, 53.07 cM
• Alliance: Pde6b^rd10 page

Mutation origin

• Strain of Origin: CXB1/ByJ

Mutation description

• Allele Type: Spontaneous
• Mutation: Nucleotide substitutions
• Mutation details: An initial complementation test with Pde6b rd1 demonstrated allelism. Sequence analysis shows that the rd10 mutation is caused by a missense mutation in exon 13, which encodes the beta subunit of the protein. (J:75095)
• Inheritance: Recessive

Disease models

Expression

In Mice Carrying this Mutation:	4 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pde6b Mutation: 122 strains or lines available

References

• Original: J:75095 Chang B, et al., Retinal degeneration mutants in the mouse. Vision Res. 2002 Feb;42(4):517-25
• All: 163 reference(s)