Chst10^tm1Msch
Targeted Allele Detail

Summary

• Symbol: Chst10^tm1Msch
• Name: carbohydrate sulfotransferase 10; targeted mutation 1, Melitta Schachner
• MGI ID: MGI:2388475
• Synonyms: ST-
• Gene: Chst10 Location: Chr1:38902948-38937242 bp, - strand Genetic Position: Chr1, 17.24 cM
• Alliance: Chst10^tm1Msch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:79015
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced with a neomycin selection cassette. Protein product was undetected by Western blot analysis of brain tissue obtained from homozygous mutant mice. (J:79015)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chst10 Mutation: 22 strains or lines available

References

• Original: J:79015 Senn C, et al., Mice Deficient for the HNK-1 Sulfotransferase Show Alterations in Synaptic Efficacy and Spatial Learning and Memory. Mol Cell Neurosci. 2002 Aug;20(4):712
• All: 4 reference(s)