Rr275254tm2.1Dhr
Targeted Allele Detail
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Symbol: |
Rr275254tm2.1Dhr |
Name: |
regulatory region 275254; targeted mutation 2.1, David H Raulet |
MGI ID: |
MGI:2388608 |
Synonyms: |
E-, ECgamma1-, Trgc1tm2.1Dhr |
Gene: |
Rr275254 Location: Chr13:19402601-19404400 bp, . strand Genetic Position: Chr13, Syntenic
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Alliance: |
Rr275254tm2.1Dhr page
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Germline Transmission: |
Earliest citation of germline transmission:
J:75624
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Parent Cell Line: |
J1 (ES Cell)
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Strain of Origin: |
129S4/SvJae
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Allele Type: |
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Targeted (Modified regulatory region, Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: This allele is derived from Rr275254tm2Dhr. The loxP site flanked neomycin resistance gene cassette substituted in place of the Ecgamma 1 enhancer element was removed by crossing Tcrg-C1tm2Dhr animals to a cre-deleter strain.
(J:75624)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rr275254 Mutation: |
0 strains or lines available
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Original: |
J:75624 Xiong N, et al., Redundant and unique roles of two enhancer elements in the TCRgamma locus in gene regulation and gammadelta T cell development. Immunity. 2002 Mar;16(3):453-63 |
All: |
1 reference(s) |
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