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Rr275254tm2.1Dhr
Targeted Allele Detail
Summary
Symbol: Rr275254tm2.1Dhr
Name: regulatory region 275254; targeted mutation 2.1, David H Raulet
MGI ID: MGI:2388608
Synonyms: E-, ECgamma1-, Trgc1tm2.1Dhr
Gene: Rr275254  Location: Chr13:19402601-19404400 bp, . strand  Genetic Position: Chr13, Syntenic
Alliance: Rr275254tm2.1Dhr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:75624
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Modified regulatory region, Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThis allele is derived from Rr275254tm2Dhr. The loxP site flanked neomycin resistance gene cassette substituted in place of the Ecgamma 1 enhancer element was removed by crossing Tcrg-C1tm2Dhr animals to a cre-deleter strain. (J:75624)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rr275254 Mutation:  0 strains or lines available
References
Original:  J:75624 Xiong N, et al., Redundant and unique roles of two enhancer elements in the TCRgamma locus in gene regulation and gammadelta T cell development. Immunity. 2002 Mar;16(3):453-63
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory