Tg(Lck-Tnfsf4)1Nish
Transgene Detail

Summary

• Symbol: Tg(Lck-Tnfsf4)1Nish
• Name: transgene insertion 1, Naoto Ishii
• MGI ID: MGI:2388725
• Synonyms: OX40L-Tg, OX40L-Tg1, OX40L-TgL
• Transgene: Tg(Lck-Tnfsf4)1Nish Location: unknown
• Alliance: Tg(Lck-Tnfsf4)1Nish page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Lck-Tnfsf4)1Nish expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Tnfsf4 (MGI:104511)

• Mutation details: The transgenic construct contained a Tnfsf4 cDNA adjoined to an Lck proximal promoter to drive expression in thymocytes. Overexpression was determined by flow cytometric analysis of thymocytes obtained from transgenice mice. (J:79528)

Disease models

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:79528 Murata K, et al., Constitutive OX40/OX40 ligand interaction induces autoimmune-like diseases. J Immunol. 2002 Oct 15;169(8):4628-36
• All: 8 reference(s)