About   Help   FAQ
Bmd13C57BL/6J
QTL Variant Detail
Summary
QTL variant: Bmd13C57BL/6J
Name: bone mineral density 13; C57BL/6J
MGI ID: MGI:2389169
QTL: Bmd13  Location: Chr13:56629249-56629397 bp  Genetic Position: Chr13, cM position of peak correlated region/allele: 21.73 cM
QTL Note: genome coordinates based on the boundaries of the QTL region
Variant
origin
Strain of Specimen:  C57BL/6J
Variant
description
Allele Type:    QTL
Inheritance:    Other (see notes)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Notes
Bmd13 exhibits additive inheritance.

Mapping and Phenotype information for this QTL, its variants and associated markers

J:78754

Linkage analysis was performed on 986 (C57BL/6J x C3H/HeJ)F2 female animals using 107 microsatellite markers to identify QTLs associated with bone mineral density (BMD). Parental strain C3H/HeJ exhibits higher bone mineral density values compared to C57BL/6J. Bmd13 mapped to 35 cM on mouse Chromosome 13 with a peak LOD=7.73 at D13Mit13 in linkage to femoral BMD. C3H/HeJ-derived alleles confer an additively-inherited increase in BMD at Bmd13.

References
Original:  J:78754 Beamer WG, et al., Quantitative trait loci for femoral and lumbar vertebral bone mineral density in C57BL/6J and C3H/HeJ inbred strains of mice. J Bone Miner Res. 2001 Jul;16(7):1195-206
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/22/2024
MGI 6.24
The Jackson Laboratory