Ephb6^tm1Tom
Targeted Allele Detail

Summary

• Symbol: Ephb6^tm1Tom
• Name: Eph receptor B6; targeted mutation 1, Toshimitsu Matsui
• MGI ID: MGI:2389310
• Gene: Ephb6 Location: Chr6:41582416-41597443 bp, + strand Genetic Position: Chr6, 19.77 cM
• Alliance: Ephb6^tm1Tom page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:79747
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A portion of exon 1 and all of exons 2 and 3 were replaced by a floxed neo cassette inserted by homologous recombination. The deleted region included the translational start codon. (J:79747)

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ephb6 Mutation: 54 strains or lines available

References

• Original: J:79747 Shimoyama M, et al., Developmental expression of EphB6 in the thymus: lessons from EphB6 knockout mice. Biochem Biophys Res Commun. 2002 Oct 18;298(1):87
• All: 2 reference(s)