Msh2^tm1Tts
Targeted Allele Detail

Summary

• Symbol: Msh2^tm1Tts
• Name: mutS homolog 2; targeted mutation 1, Teruhisa Tsuzuki
• MGI ID: MGI:2389314
• Synonyms: MSH2^-
• Gene: Msh2 Location: Chr17:87979960-88031141 bp, + strand Genetic Position: Chr17, 57.87 cM
• Alliance: Msh2^tm1Tts page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:79732
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Disruption caused by insertion of vector
• Mutation details: A portion of exon 13 and all of exon 14 were replaced by a neomycin selection cassette inserted by homologous recombination. (J:79732)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Msh2 Mutation: 95 strains or lines available

References

• Original: J:79732 Egashira A, et al., Mutational specificity of mice defective in the MTH1 and/or the MSH2 genes. DNA Repair (Amst). 2002 Nov 3;1(11):881-93
• All: 2 reference(s)