Tg(Nell1)1Ting
Transgene Detail

Summary

• Symbol: Tg(Nell1)1Ting
• Name: transgene insertion 1, Kang Ting
• MGI ID: MGI:2389416
• Transgene: Tg(Nell1)1Ting Location: unknown
• Alliance: Tg(Nell1)1Ting page

Transgene origin

• Strain of Origin: C57BL/6 x C3H

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Nell1)1Ting expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Neil1 (367090)

  Neil1

  (MGI:1920024)

• Mutation details: A transgenic construct containing a CMV promoter, rat Nell1 cDNA, and an SV40 polyadenylation signal was randomly integrated into the murine genome. Southern blot analysis revealed 50 to 100 insertions of the construct in the founder line and expression was confirmed by RT-PCR and immunohistochemical analysis. (J:79106)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:79106 Zhang X, et al., Craniosynostosis in transgenic mice overexpressing Nell-1. J Clin Invest. 2002 Sep;110(6):861-70
• All: 7 reference(s)