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Dob9C57BL/6J
QTL Variant Detail
Summary
QTL variant: Dob9C57BL/6J
Name: dietary obesity 9; C57BL/6J
MGI ID: MGI:2389473
QTL: Dob9  Location: Chr15:26035680-37781301 bp  Genetic Position: Chr15, cM position of peak correlated region/allele: 17.76 cM
Variant
origin
Strain of Specimen:  C57BL/6J
Variant
description
Allele Type:    QTL
Inheritance:    Not Specified
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:35460

Analysis of 143 male (CAST/Ei x C57BL/6J)F2 mice indicates that a QTL (Dob9) affecting dietary obesity is located on Chromosome 15 between D15Mit9 and D15Mit22 with peak LOD scores of 4.3, 3.1, and 3.7 for mesenteric adipose depot weight, average epididymal adipose depot weight, and body weight respectively. Authors further state that Dob9 maps very close to Dob3 in the SWR/J x AKR/J cross and Mob4 in BSB mice.

References
Original:  J:35460 York B, et al., Sensitivity to dietary obesity linked to a locus on chromosome 15 in a CAST/Ei x C57BL/6J F2 intercross. Mamm Genome. 1996 Sep;7(9):677-81
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory