Tg(Hsp70-1-cre)1Arge
Transgene Detail

Summary

• Symbol: Tg(Hsp70-1-cre)1Arge
• Name: transgene insertion 1, Argiris Efstratiadis
• MGI ID: MGI:2389571
• Synonyms: Hs-cre1, Hspa1b-cre1
• Transgene: Tg(Hsp70-1-cre)1Arge Location: unknown
• Alliance: Tg(Hsp70-1-cre)1Arge page

Transgene origin

• Strain of Origin: C57BL/6J x CBA

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Hsp70-1-cre)1Arge expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Hspa1b (MGI:99517)

• Mutation details: A sequence fragment from the murine Hsp70-1 locus encompassing 655 bp of the 5' flanking and noncoding sequence was adjoined to sequence encoding cre recombinase. Two tandem integrations of the transgenic construct were identified in the founder line. Transgene expression occurred early in embryogenesis, resulting in the production of progeny exhibiting complete recombination of reporter constructs. (J:60711)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Hspa1b (mouse) Summary of all recombinase alleles driven by Hspa1b. Alliance mouse Hspa1b gene page

Tumor Data

List all tumor models in MMHCdb carrying Tg(Hsp70-1-cre)1Arge

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:60711 Dietrich P, et al., Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes. Mamm Genome. 2000 Mar;11(3):196-205
• All: 13 reference(s)