Igf1r^tm2Arge
Targeted Allele Detail

Summary

• Symbol: Igf1r^tm2Arge
• Name: insulin-like growth factor I receptor; targeted mutation 2, Argiris Efstratiadis
• MGI ID: MGI:2389580
• Synonyms: Igf1r^c, Igf1r^lox, IGF1R^Lox
• Gene: Igf1r Location: Chr7:67602575-67883416 bp, + strand Genetic Position: Chr7, 37.27 cM
• Alliance: Igf1r^tm2Arge page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:60711
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 3 was flanked by a floxed neo cassette in intron 2 and a single loxP site in intron 3. (J:60711)

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Igf1r Mutation: 88 strains or lines available

References

• Original: J:60711 Dietrich P, et al., Conditional mutagenesis in mice with heat shock promoter-driven cre transgenes. Mamm Genome. 2000 Mar;11(3):196-205
• All: 70 reference(s)