About   Help   FAQ
Tg(Vav-BCL2)69Jad
Transgene Detail
Summary
Symbol: Tg(Vav-BCL2)69Jad
Name: transgene insertion 69, Jerry M Adams
MGI ID: MGI:2429387
Synonyms: Bcl20, hBcl-2 Tg, Tg(Vav-BCL2)1Jad, Vav2-hBcl-2, vav-bcl-2, vav-Bcl2, vav-bcl-2-69
Transgene: Tg(Vav-BCL2)69Jad  Location: unknown  
Alliance: Tg(Vav-BCL2)69Jad page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Vav-BCL2)69Jad expresses 1 gene
 
Mutation detailsOverexpression of human BCL2 cDNA was driven by the mouse Vav promoter, which drives expression predominantly in nucleated cells of hematopoietic tissue. (J:59085)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
References
Original:  J:59085 Ogilvy S, et al., Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14943-8
All:  109 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/19/2024
MGI 6.24
The Jackson Laboratory