Basp1^tm1Crni
Targeted Allele Detail

Summary

• Symbol: Basp1^tm1Crni
• Name: brain abundant, membrane attached signal protein 1; targeted mutation 1, Pico Caroni
• MGI ID: MGI:2429495
• Synonyms: CAP23^-
• Gene: Basp1 Location: Chr15:25363363-25413850 bp, - strand Genetic Position: Chr15, 9.16 cM
• Alliance: Basp1^tm1Crni page

Neuromuscular junction abnormalities in Basp1^tm1Crni/Basp1^tm1Crni mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:63023
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The endogenous locus was disrupted by the insertion of a cassette containing NLS-lacZ and neo. Endogenous expression was undetected by immunocytochemical and in situ hybridization analyses of homozygous mutant mice. (J:63023)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Basp1 Mutation: 14 strains or lines available

References

• Original: J:63023 Frey D, et al., Shared and unique roles of CAP23 and GAP43 in actin regulation, neurite outgrowth, and anatomical plasticity. J Cell Biol. 2000 Jun 26;149(7):1443-54
• All: 1 reference(s)