Basp1^{tm2(Gap43)Crni}
Targeted Allele Detail

Summary

• Symbol: Basp1^{tm2(Gap43)Crni}
• Name: brain abundant, membrane attached signal protein 1; targeted mutation 2, Pico Caroni
• MGI ID: MGI:2429496
• Synonyms: CAP23^gap43
• Gene: Basp1 Location: Chr15:25363363-25413850 bp, - strand Genetic Position: Chr15, 9.16 cM
• Alliance: Basp1^{tm2(Gap43)Crni} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:63023
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout)
• Mutation: Insertion
• Mutation details: A construct, containing Gap43 sequence followed by IRES-NLS-LacZ and neo, was inserted at the endogenous locus. Northern blot analysis of homozygous mutant mice confirmed the presence of Gap43 transcript produced from the inserted sequence as well as the absence of Basp1 transcript. (J:63023)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Basp1 Mutation: 13 strains or lines available

References

• Original: J:63023 Frey D, et al., Shared and unique roles of CAP23 and GAP43 in actin regulation, neurite outgrowth, and anatomical plasticity. J Cell Biol. 2000 Jun 26;149(7):1443-54
• All: 1 reference(s)