Tria2^BALB/cHeA
QTL Variant Detail

Summary

• QTL variant: Tria2^BALB/cHeA
• Name: T cell receptor induced activation 2; BALB/cHeA
• MGI ID: MGI:2429541
• QTL: Tria2 Location: Chr15:61859141-61859281 bp Genetic Position: Chr15, cM position of peak correlated region/allele: 26.19 cM
• QTL Note: genome coordinates based on the marker associated with the peak LOD score

Variant origin

• Strain of Specimen: BALB/cHeA

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:36501

The CcS-4 strain was found to exhibit a proliferation of T cells in response to Cd3 mAb. F2 hybrids between responder CcS-4 and parental BALB/c mice were examined to localize quantitative trait loci involved with control of this response. Tria2 was localized on mouse Chromosome 15 associated with marker D15Mit17 (P = 0.000099).

References

• Original: J:36501 Havelkova H, et al., Genetic control of T-cell proliferative response in mice linked to chromosomes 11 and 15. Immunogenetics. 1996;44(6):475-7
• All: 1 reference(s)