Pou4f3^tm1Whk
Targeted Allele Detail

Summary

• Symbol: Pou4f3^tm1Whk
• Name: POU domain, class 4, transcription factor 3; targeted mutation 1, William H Klein
• MGI ID: MGI:2429629
• Synonyms: Brn3c(AP), Pou4f3^tm1Kln
• Gene: Pou4f3 Location: Chr18:42527662-42529158 bp, + strand Genetic Position: Chr18, 22.58 cM, cytoband B3-E1
• Alliance: Pou4f3^tm1Whk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:73779
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The endogenous locus was disrupted by the insertion of a construct containing human placental alkaline phosphatase (ALPP) followed by a neo cassette. (J:73779)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pou4f3 Mutation: 25 strains or lines available

References

• Original: J:73779 Wang SW, et al., Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth. Development. 2002 Jan;129(2):467-77
• All: 1 reference(s)