Adgre1^tm1(cre)Kpf
Targeted Allele Detail

Summary

• Symbol: Adgre1^tm1(cre)Kpf
• Name: adhesion G protein-coupled receptor E1; targeted mutation 1, Klaus Pfeffer
• MGI ID: MGI:2429642
• Synonyms: F4/80^-, F4/80-Cre, F4/80^Cre
• Gene: Adgre1 Location: Chr17:57665691-57790527 bp, + strand Genetic Position: Chr17, 29.8 cM
• Alliance: Adgre1^tm1(cre)Kpf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:79911
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutations: Insertion, Intragenic deletion
• Adgre1^tm1(cre)Kpf expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Adgre1 (MGI:106912)

• Mutation details: The insertion of a targeting vector replaced endogenous coding sequence with cre and neo. Northern blot and immunohistochemical analyses indicated the absence of transcript and protein in homozygous mutant mice. Recombination of a floxed reporter verified translation of a functional cre recombinase. (J:79911)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Adgre1 (mouse) Summary of all recombinase alleles driven by Adgre1. Alliance mouse Adgre1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adgre1 Mutation: 79 strains or lines available

References

• Original: J:79911 Schaller E, et al., Inactivation of the F4/80 glycoprotein in the mouse germ line. Mol Cell Biol. 2002 Nov;22(22):8035-43
• All: 8 reference(s)