Tbp^tm1Idvd
Targeted Allele Detail

Summary

• Symbol: Tbp^tm1Idvd
• Name: TATA box binding protein; targeted mutation 1, Irwin Davidson
• MGI ID: MGI:2429772
• Synonyms: TBP^-
• Gene: Tbp Location: Chr17:15720150-15737689 bp, + strand Genetic Position: Chr17, 8.95 cM
• Alliance: Tbp^tm1Idvd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:79959
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Exon 3 was disrupted by the insertion of a hygromycin selection cassette. Immunostaining of homozygous mutant blastocysts indicated a lack of endogenous protein. (J:79959)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbp Mutation: 10 strains or lines available

References

• Original: J:79959 Martianov I, et al., RNA polymerase II transcription in murine cells lacking the TATA binding protein. Science. 2002 Nov 1;298(5595):1036-9
• All: 2 reference(s)