Tg(Mpz-cre)1Brn
Transgene Detail

Summary

• Symbol: Tg(Mpz-cre)1Brn
• Name: transgene insertion 1, Anton Berns
• MGI ID: MGI:2445228
• Synonyms: P0A-Cre, P0 Cre, POCre^A, Tg(P0-Cre)1Gth
• Transgene: Tg(Mpz-cre)1Brn Location: unknown
• Alliance: Tg(Mpz-cre)1Brn page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Mpz-cre)1Brn expression driven by 1 gene
  Transgene expression driven by:
  

  Organism

  Driver Gene

  Homolog in Mouse

  Note

  rat

  Mpz (24564)

  Mpz	(MGI:103177)

• Mutation details: This transgene expresses Cre recombinase under the control of a rat Mpz promoter. This promoter is active in many, but not all, myelinating Schwann cells. (J:80158)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Mpz (rat) Summary of all recombinase alleles driven by Mpz. Comparative matrix view of recombinase activities Alliance rat Mpz gene page

Disease models

Tumor Data

List all tumor models in MMHCdb carrying Tg(Mpz-cre)1Brn

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

Four founders were originally designated as P0Cre^A-D.

References

• Original: J:80158 Akagi K, et al., Cre-mediated somatic site-specific recombination in mice. Nucleic Acids Res. 1997 May 1;25(9):1766-73
• All: 9 reference(s)