St3gal3^tm1Jxm
Targeted Allele Detail

Summary

• Symbol: St3gal3^tm1Jxm
• Name: ST3 beta-galactoside alpha-2,3-sialyltransferase 3; targeted mutation 1, Jamey Marth
• MGI ID: MGI:2445404
• Synonyms: ST3Gal-III^delta
• Gene: St3gal3 Location: Chr4:117789351-117992111 bp, - strand Genetic Position: Chr4, 53.84 cM, cytoband D1
• Alliance: St3gal3^tm1Jxm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:80119
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The exon encoding the transmembrane domain was replaced with a single loxP site after the insertion of loxP sites and subsequent expression of cre recombinase in ES cells. (J:80119)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any St3gal3 Mutation: 34 strains or lines available

References

• Original: J:80119 Ellies LG, et al., Sialyltransferase specificity in selectin ligand formation. Blood. 2002 Nov 15;100(10):3618-25
• All: 8 reference(s)