Cpb2^tm1Efp
Targeted Allele Detail

Summary

• Symbol: Cpb2^tm1Efp
• Name: carboxypeptidase B2; targeted mutation 1, Edward F Plow
• MGI ID: MGI:2445419
• Synonyms: pCPB^-
• Gene: Cpb2 Location: Chr14:75479727-75520995 bp, + strand Genetic Position: Chr14, 39.73 cM, cytoband D2
• Alliance: Cpb2^tm1Efp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:80114
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Exon 2 was disrupted by the insertion of a neomycin selection cassette. No transcript was detected by Northern blot analysis of homozygous mutant liver. (J:80114)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cpb2 Mutation: 31 strains or lines available

References

• Original: J:80114 Swaisgood CM, et al., In vivo regulation of plasminogen function by plasma carboxypeptidase B. J Clin Invest. 2002 Nov;110(9):1275-82
• All: 3 reference(s)