Med21^tm1Ryng
Targeted Allele Detail

Summary

• Symbol: Med21^tm1Ryng
• Name: mediator complex subunit 21; targeted mutation 1, Richard A Young
• MGI ID: MGI:2445456
• Synonyms: Srb7^-
• Gene: Med21 Location: Chr6:146544077-146552098 bp, + strand Genetic Position: Chr6, 77.7 cM
• Alliance: Med21^tm1Ryng page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:57760
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were replaced with a selection cassette (containing either neomycin or hygromycin) through homologous recombination. (J:57760)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Med21 Mutation: 18 strains or lines available

References

• Original: J:57760 Tudor M, et al., Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice. Genes Dev. 1999 Sep 15;13(18):2365-8
• All: 1 reference(s)