Summary |
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Variant origin |
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Variant description |
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Phenotypes |
View phenotypes and curated references for all genotypes (concatenated display).
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Expression |
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Notes |
Mapping and Phenotype information for this QTL, its variants and associated markersJ:48957NON/LtHl inbred mice were selected for impaired glucose tolerance and NZO/Hl inbreds were selected for polygenic obesity, respectively. Their male F1 progeny consistently developed NIDDM (non-insulin-dependent diabetes mellitus). A total of 193 (NZO/Hlx NON/LtHl)F2 and 201 (NON/LtHl x NZO/Hl)F2 mice were informative in identifying NIDDM susceptibility trait loci. Nidd3 was contributed by the NON/LtHl background and mapped to an interval of mouse Chromosome 11 that contained a peak at marker D11Mit261 (LOD 8.9) and a peak at marker D11Mit41 (LOD 11.1). |
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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