Tarbp2^tm1Reb
Targeted Allele Detail

Summary

• Symbol: Tarbp2^tm1Reb
• Name: TARBP2, RISC loading complex RNA binding subunit; targeted mutation 1, Robert E Braun
• MGI ID: MGI:2445673
• Synonyms: Tarbp2^-, Tarbp2^tm1Junz
• Gene: Tarbp2 Location: Chr15:102426627-102432111 bp, + strand Genetic Position: Chr15, 57.65 cM, cytoband F
• Alliance: Tarbp2^tm1Reb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:55515
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Exons 3 through 9 were replaced with a lacZ reporter construct via homologous recombination in AK7 ES cells. (J:55515)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tarbp2 Mutation: 22 strains or lines available

References

• Original: J:55515 Zhong J, et al., A double-stranded RNA binding protein required for activation of repressed messages in mammalian germ cells. Nat Genet. 1999 Jun;22(2):171-4
• All: 3 reference(s)