Slc27a4^wrfr
Spontaneous Allele Detail

Summary

• Symbol: Slc27a4^wrfr
• Name: solute carrier family 27 (fatty acid transporter), member 4; wrinkle free
• MGI ID: MGI:2445864
• Synonyms: Fatp4^-
• Gene: Slc27a4 Location: Chr2:29692646-29707534 bp, + strand Genetic Position: Chr2, 20.64 cM, cytoband B
• Alliance: Slc27a4^wrfr page

Histological analysis of the Slc27a4^wrfr/Slc27a4^wrfr mouse

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Spontaneous
• Mutation: Transposon insertion
• Mutation details: This mutation is an insertion of a B2-type murine retrotransposon into the third exon of the gene. Northern analysis failed to detect mRNA for this gene in mutant mice. (J:83282)
• Inheritance: Recessive

Disease models

Expression

In Mice Carrying this Mutation:	14 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc27a4 Mutation: 37 strains or lines available

References

• Original: J:83282 Moulson CL, et al., Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5274-9
• All: 12 reference(s)