Kitl^Sl-28R
Chemically induced Allele Detail

Summary

• Symbol: Kitl^Sl-28R
• Name: kit ligand; steel 28 Oak Ridge
• MGI ID: MGI:2445945
• Gene: Kitl Location: Chr10:99851492-99936278 bp, + strand Genetic Position: Chr10, 51.4 cM
• Alliance: Kitl^Sl-28R page

Mutation origin

• Strain of Origin: 101/Rl

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This allele comprises an T-to-A transversion resulting in an isoleucine to asparagine substitution at position 118 (143 in pre-protein) (p.I118N, p.I143N). (J:80496)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kitl Mutation: 94 strains or lines available

References

• Original: J:80496 Rajaraman S, et al., An allelic series of mutations in the kit ligand gene of mice. I. Identification of point mutations in seven ethylnitrosourea-induced Kitl(Steel) alleles. Genetics. 2002 Sep;162(1):331-40
• All: 3 reference(s)