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Crip3tm1Mjb
Targeted Allele Detail
Summary
Symbol: Crip3tm1Mjb
Name: cysteine-rich protein 3; targeted mutation 1, Michael J Bevan
MGI ID: MGI:2445952
Synonyms: TLP-
Gene: Crip3  Location: Chr17:46739852-46742702 bp, + strand  Genetic Position: Chr17, 22.9 cM, cytoband C
Alliance: Crip3tm1Mjb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:72942
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129S/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe entire coding region was replaced with a construct containing a beta-galactosidase gene followed by neo. Neither transcript nor protein was detected in homozygous mutant mice by Northern blot or immunohistochemical staining. (J:72942)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Crip3 Mutation:  22 strains or lines available
Notes
ES cell line = AK7 (129S4/SvJaeSor) or TC-1 (129S6/SvEvTac).
References
Original:  J:72942 Kirchner J, et al., Identification and Characterization of Thymus LIM Protein: Targeted Disruption Reduces Thymus Cellularity. Mol Cell Biol. 2001 Dec;21(24):8592-604
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory