Crip3^tm1Mjb
Targeted Allele Detail

Summary

• Symbol: Crip3^tm1Mjb
• Name: cysteine-rich protein 3; targeted mutation 1, Michael J Bevan
• MGI ID: MGI:2445952
• Synonyms: TLP^-
• Gene: Crip3 Location: Chr17:46739852-46742702 bp, + strand Genetic Position: Chr17, 22.9 cM, cytoband C
• Alliance: Crip3^tm1Mjb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:72942
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129S/Sv

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire coding region was replaced with a construct containing a beta-galactosidase gene followed by neo. Neither transcript nor protein was detected in homozygous mutant mice by Northern blot or immunohistochemical staining. (J:72942)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Crip3 Mutation: 22 strains or lines available

Notes

ES cell line = AK7 (129S4/SvJaeSor) or TC-1 (129S6/SvEvTac).

References

• Original: J:72942 Kirchner J, et al., Identification and Characterization of Thymus LIM Protein: Targeted Disruption Reduces Thymus Cellularity. Mol Cell Biol. 2001 Dec;21(24):8592-604
• All: 1 reference(s)