Tg(Eno2-Hgf)1Tnak
Transgene Detail

Summary

• Symbol: Tg(Eno2-Hgf)1Tnak
• Name: transgene insertion 1, Toshikazu Nakamura
• MGI ID: MGI:2446529
• Synonyms: NSE-HGF-Tg
• Transgene: Tg(Eno2-Hgf)1Tnak Location: unknown
• Alliance: Tg(Eno2-Hgf)1Tnak page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Eno2-Hgf)1Tnak expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Hgf (24446)

  Hgf	(MGI:96079)

• Mutation details: The full length rat hepatocyte growth factor (Hgf) cDNA was tagged with the KT3 epitope,followed by a polyadenylation signal, and inserted downstream of the neuron specific Eno2 promoter. RNAse protection showed expression of the Hgf transgene in the brain and spinal cord. (J:78090, J:128738)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:78090 Sun W, et al., Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS. J Neurosci. 2002 Aug 1;22(15):6537-48
• All: 5 reference(s)