Stam2^tm1Sug
Targeted Allele Detail

Summary

• Symbol: Stam2^tm1Sug
• Name: signal transducing adaptor molecule (SH3 domain and ITAM motif) 2; targeted mutation 1, Kazuo Sugamura
• MGI ID: MGI:2446571
• Synonyms: STAM2^-
• Gene: Stam2 Location: Chr2:52582213-52632212 bp, - strand Genetic Position: Chr2, 30.41 cM
• Alliance: Stam2^tm1Sug page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:80617
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: The endogenous allele was disrupted using molecular techniques. Normal protein was undetected by Western blot analysis of homozygous mutant thymocyte immunoprecipitates. (J:80617)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Stam2 Mutation: 56 strains or lines available

References

• Original: J:80617 Yamada M, et al., Signal-Transducing Adaptor Molecules STAM1 and STAM2 Are Required for T-Cell Development and Survival. Mol Cell Biol. 2002 Dec;22(24):8648-58
• All: 1 reference(s)