Tg(Gata1-cre)1Sho
Transgene Detail

Summary

• Symbol: Tg(Gata1-cre)1Sho
• Name: transgene insertion 1, Stuart Orkin
• MGI ID: MGI:2446599
• Synonyms: GATA1-Cre
• Transgene: Tg(Gata1-cre)1Sho Location: unknown
• Alliance: Tg(Gata1-cre)1Sho page

Transgene origin

• Strain of Origin: CD-1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Gata1-cre)1Sho expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gata1 (MGI:95661)

• Mutation details: Sequence encoding cre recombinase was adjoined to the murine Gata1 promoter region. The expanded expression pattern (relative to the endogenous Gata1 gene) has been attributed to leaky cre expression during an early stage of embryogenesis. While the Gata1 promoter was putatively a hematopoietic-specific promoter, efficient cre mediated excision has been observed in germ cells. (J:64291)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gata1 (mouse) Summary of all recombinase alleles driven by Gata1. Comparative matrix view of recombinase activities Alliance mouse Gata1 gene page

Expression

In Mice Carrying this Mutation:

20 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:64291 Mao X, et al., Improved reporter strain for monitoring Cre recombinase-mediated DNA excisions in mice. Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):5037-42
• All: 26 reference(s)