Summary |
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Variant origin |
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Variant description |
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Notes |
Candidate Genes
In order to elicudate whether or not Scd1 is the gene responsible for hepatocarcinogenesis susceptibility QTL Hcs6, 179 animals from a (BALB/c x C3H/HeJ)F2 cross were typed for markers on mouse Chromosome 19 to observe the segregation of Scd1 and Hcs6. No linkage was observed, therefore the gene responsible for Hcs6 is not Scd1.
Mapping and Phenotype information for this QTL, its variants and associated markersJ:20738Quantitative trait locus analysis was used to find loci involved in hepatocarcinogenesis susceptibility in 106 male progeny from the (C3H/He x M. spretus)F1 x C57BL/6JBy backcross. One locus, Hcs6, maps to Chromosome 19 in the region of D19Mit27 with a peak LOD score of 2.8 and P = 0.0004. |
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/10/2024 MGI 6.24 |
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