Afw11^DBA/2
QTL Variant Detail

Summary

• QTL variant: Afw11^DBA/2
• Name: abdominal fat weight QTL 11; DBA/2
• MGI ID: MGI:2446848
• QTL: Afw11 Location: unknown Genetic Position: ChrX, Syntenic

Variant origin

• Strain of Specimen: DBA/2

Variant description

• Allele Type: QTL

Notes

Trait Annotation
(using the Vertebrate Trait Ontology)

organism trait

body size trait

body fat mass VT:0010482

affect on abdominal fat weight - J:66233

Mapping and Phenotype information for this QTL, its variants and associated markers

J:66233

QTL effecting body weight, obesity and muscle weight were found on mouse Chromosomes 1, 4, 5, 7, 11, 12, 13, and 17 and for leptin on 14 and insulin on chromosome 4. The cross used in the genome wide scan included approximately 400 F2 mice from a (DU6i x DBA/2)F1 intercross. DU6i is a strain selected for high body weight. 93 microsatellite markers were analyzed in the genome wide scan. Locations of the QTL were provided by the authors and may not be equivalent to the closest microsatellites. Abdominalfat weight QTL 11 and liver weight QTL 8 mapped to the mouse X Chromosome at cM positions 17 and 44 respectively.

References

• Original: J:66233 Brockmann GA, et al., Single QTL effects, epistasis, and pleiotropy account for two-thirds of the phenotypic F(2) variance of growth and obesity in DU6i x DBA/2 mice. Genome Res. 2000 Dec;10(12):1941-57
• All: 1 reference(s)