Bdln1^{M. spretus}
QTL Variant Detail

Summary

• QTL variant: Bdln1^{M. spretus}
• Name: body length 1; M. spretus
• MGI ID: MGI:2446859
• QTL: Bdln1 Location: ChrX:58702106-58702218 bp Genetic Position: ChrX, Syntenic

Variant origin

• Strain of Specimen: M. spretus

Variant description

• Allele Type: QTL
• Mutation: Undefined
• This allele confers increased body length compared to C57BL/6J. (J:32015)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:32015

In order to isolate a locus linked to body length (Bdln) in mice, authors typed progeny of a BSB [(C57BL/6J x M. spretus)F1 x M. spretus] interspecific backcross using quantitative trait analysis. 252 mice were typed for 148 markers covering all chromosomes, except the Y Chromosome. Significant association of body length with several linked markers on the X Chromosome, specifically in the area between markers DXMit57 and DXUcla2 was found. A

peak LOD of 5.5 (with data from both sexes) was found at the DXMit73 locus. Male and female mice of the M. spretus genotype at the DXMit73 locus had approximately 4% and 3.5% increases respectively in body length as compared to mice of the C57BL/6J genotype.

References

• Original: J:32015 Lembertas AV, et al., A locus on the X chromosome is linked to body length in mice. Mamm Genome. 1996 Mar;7(3):171-3
• All: 1 reference(s)