Bw2^C3H/He
QTL Variant Detail

Summary

• QTL variant: Bw2^C3H/He
• Name: body weight QTL 2; C3H/He
• MGI ID: MGI:2446868
• QTL: Bw2 Location: unknown Genetic Position: ChrX, Syntenic

Variant origin

• Strain of Specimen: C3H/He

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:29849

By quantitative trait mapping using MAPMAKER/QTL the authors reported that regions on mouse Chromosome X were significantly associated with adult body weight in mice. Three loci, Bw1, Bw2 and Bw3 were mapped using two crosses.

In the first cross ((C3H/He x M. spretus))F1 females were mated to C57BL/6J males. In the first cross Bw1 mapped to a region defined proximally by DXMit57 and distally by DXMit48 and Bw2 by DXMit109 and DXMit16.

In the second cross ((A/J x M. spretus))F1 females were mated to C57BL/6J males. In this second cross Bw1 was mapped to a region defined proximally by DXNds1, Bw2 by DXMit60 and DXMit16 and Bw3 by DXMit3 and DXMit12.

01.07.2015 Curator Note: Because Bw1 and Bw2 were originally mapped here in the first cross, which differs from the second cross, we consider the second cross a separate mapping experiment and have named the QTL identified as Bw33 (defined proximally by DXNds1) and Bw34 (defined by DXMit60 and DXMit16), respectively.

References

• Original: J:29849 Dragani TA, et al., Mapping of body weight loci on mouse chromosome X. Mamm Genome. 1995 Nov;6(11):778-81
• All: 1 reference(s)