Tshp2^SM/J
QTL Variant Detail

Summary

• QTL variant: Tshp2^SM/J
• Name: tooth shape 2; SM/J
• MGI ID: MGI:2447039
• QTL: Tshp2 Location: unknown Genetic Position: Chr1, Syntenic

Variant origin

• Strain of Specimen: SM/J

Variant description

• Allele Type: QTL

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:76126

76 polymorphic microsatellite markers at an average distance of 27.5 cM were screened in 535 (SM/J x LG/J)F2 animals to identify QTLs associated with tooth development. Parental inbred strain LG/J exhibits larger body size compared to SM/J. QTLs affecting tooth shape, Tshp1 and Tshp2, mapped to mouse Chromosome 1. The Tshp1 interval spans 58.7 cM - 81.6 cM and the Tshp2 interval is centered around 81.6 cM on chromosome 1. Both tooth size QTLs exceed the P<0.001 significance threshold of LOD=4.185.

References

• Original: J:76126 Workman MS, et al., Analysis of quantitative trait locus effects on the size and shape of mandibular molars in mice. Genetics. 2002 Apr;160(4):1573-86
• All: 1 reference(s)