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Tg(tetO-Pou2af1)1Pjln
Transgene Detail
Summary
Symbol: Tg(tetO-Pou2af1)1Pjln
Name: transgene insertion 1, Peter J Nielsen
MGI ID: MGI:2447124
Synonyms: tetO-BOB.1/OBF.1
Transgene: Tg(tetO-Pou2af1)1Pjln  Location: unknown  
Alliance: Tg(tetO-Pou2af1)1Pjln page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Mutation detailsA transgenic construct was generated in which a bidirectional tetracycline operator (tetO) was placed between sequences encoding Pou2af1 and luciferase. Conditional expression of both luciferase and Pou2af1 was demonstrated by the expression of a tetracycline transactivator and administration of doxycycline. (J:67362)
Phenotypes
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Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:67362 Hess J, et al., The B lymphocyte-specific coactivator BOB.1/OBF.1 is required at multiple stages of B-cell development. Mol Cell Biol. 2001 Mar;21(5):1531-9
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory