Tg(Prnp)1D4Lnq
Transgene Detail

Summary

• Symbol: Tg(Prnp)1D4Lnq
• Name: transgene insertion 1D4, Susan Lindquist
• MGI ID: MGI:2447139
• Synonyms: 1D4
• Transgene: Tg(Prnp)1D4Lnq Location: unknown
• Alliance: Tg(Prnp)1D4Lnq page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Prnp)1D4Lnq expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Prnp (MGI:97769)

• Mutation details: The entire mouse Prnp gene was used for the transgene. The 1D4 line carries 7 copies of the integrated transgene. (J:80582)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:80582 Ma J, et al., Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol. Science. 2002 Nov 29;298(5599):1781-5
• All: 2 reference(s)