Snai2^tm2Grid
Targeted Allele Detail

Summary

• Symbol: Snai2^tm2Grid
• Name: snail family zinc finger 2; targeted mutation 2, Tom Gridley
• MGI ID: MGI:2447176
• Synonyms: Slug^-, Slugh^delta1, Snai2^del1
• Gene: Snai2 Location: Chr16:14523716-14527249 bp, + strand Genetic Position: Chr16, 10.07 cM
• Alliance: Snai2^tm2Grid page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:48521
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The gene was inactivated by replacement of the entire protein coding region with a PGK-neo cassette via homologous recombination. (J:48521)

Disease models

Expression

In Mice Carrying this Mutation:	15 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Snai2^tm2Grid

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Snai2 Mutation: 35 strains or lines available

References

• Original: J:48521 Jiang R, et al., The Slug gene is not essential for mesoderm or neural crest development in mice. Dev Biol. 1998 Jun 15;198(2):277-85
• All: 19 reference(s)