Cd36tm1Frm
Targeted Allele Detail
|
|
| Symbol: |
Cd36tm1Frm |
| Name: |
CD36 molecule; targeted mutation 1, Mason W Freeman |
| MGI ID: |
MGI:2447190 |
| Synonyms: |
CD36- |
| Gene: |
Cd36 Location: Chr5:17986688-18093799 bp, - strand Genetic Position: Chr5, 8.11 cM
|
| Alliance: |
Cd36tm1Frm page
|
|
| Germline Transmission: |
Earliest citation of germline transmission:
J:80658
|
| Parent Cell Line: |
J1 (ES Cell)
|
| Strain of Origin: |
129S4/SvJae
|
|
| Allele Type: |
|
Targeted (Null/knockout) |
| Mutations: |
|
Insertion, Intragenic deletion
|
| |
|
Mutation details: The gene was disrupted by replacement of exons 3-9 with a neomycin resistance cassette via homologous recombination. Absence of gene expression in homozygous mutant animals was verified by Western blot analysis of several organ samples and primary myeloid cells.
(J:80658)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
| Carrying any Cd36 Mutation: |
34 strains or lines available
|
|
| Original: |
J:80658 Moore KJ, et al., A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid. J Biol Chem. 2002 Dec 6;277(49):47373-9 |
| All: |
31 reference(s) |
|
Analysis Tools
