Kitl^Sl-3Neu
Chemically and radiation induced Allele Detail

Summary

• Symbol: Kitl^Sl-3Neu
• Name: kit ligand; steel 3 Neuherberg
• MGI ID: MGI:2447306
• Synonyms: Mgf^Sl-3Neu
• Gene: Kitl Location: Chr10:99851492-99936278 bp, + strand Genetic Position: Chr10, 51.4 cM
• Alliance: Kitl^Sl-3Neu page

Mutation origin

• Strain of Origin: (102/El x C3H/El)F1

Mutation description

• Allele Type: Chemically and radiation induced
• Mutation: Single point mutation
• Mutation details: Sequence analysis of cDNA from mice homozygous for this allele shows an A-to-G transition, resulting in a asparagine to serine substitution at position 122 (p.N122S). (J:43966)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kitl Mutation: 94 strains or lines available

Notes

This allele was recovered among offspring of a (102/El X C3H/El)F1 male sequentially treated with 3-aminobenzamide and gamma irradiation.

References

• Original: J:43966 Graw J, et al., Detection of a point mutation (A to G) in exon 5 of the murine Mgf gene defines a novel allele at the Steel locus with a weak phenotype. Mutat Res. 1997 Sep;382(1-2):75-8
• All: 1 reference(s)