Tg(Tek-GFP/Cbfb)1Spe
Transgene Detail

Summary

• Symbol: Tg(Tek-GFP/Cbfb)1Spe
• Name: transgene insertion 1, Nancy A Speck
• MGI ID: MGI:2447350
• Synonyms: Tg(Tek-GFP/Cbfb)
• Transgene: Tg(Tek-GFP/Cbfb)1Spe Location: unknown
• Alliance: Tg(Tek-GFP/Cbfb)1Spe page

Transgene origin

• Strain of Origin: CD-1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Tek-GFP/Cbfb)1Spe expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Cbfb (MGI:99851)

• Mutation details: The transgene consists of a GPF/Cbfb fusion gene cloned in between 1.2 kb of Tek promoter sequences and a 1.7 kb Tek intronic enhancer. Transgene expression was observed in endothelial cells and fetal liver hematopoietic progenitor cells. This allele was generated on a CD1 genetic background. (J:80670)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:80670 Miller J, et al., The core-binding factor beta subunit is required for bone formation and hematopoietic maturation. Nat Genet. 2002 Dec;32(4):645-9
• All: 2 reference(s)